Pregnant women with a primary or recurrent episode of genital HSV infection who are later than 36 weeks of gestation should be treated with acyclovir (Zovirax) or valacyclovir (Valtrex) for viral suppression.
Is Valtrex safe during third trimester?
Long-term suppressive therapy can significantly reduce these outbreaks and is likely safe during pregnancy. Acyclovir (Zovirax) and valacyclovir (Valtrex) are the drugs most commonly used for herpes outbreak suppression and treatment during pregnancy. These drugs help reduce how active the virus is.
Does valacyclovir cause birth defects?
Conclusion In this large nationwide cohort, exposure to acyclovir or valacyclovir in the first trimester of pregnancy was not associated with an increased risk of major birth defects.
Does valacyclovir cross the placenta?
It does cross the placenta, and pregnant women should consult with their healthcare provider before starting acyclovir.
When should I start taking valacyclovir during pregnancy?
-Recommended regimen for HSV suppressive therapy in pregnant women with recurrent genital herpes: 500 mg orally 2 times a day starting at 36 weeks gestation.
Can you take Valtrex for cold sores while pregnant?
If the cold sores are severe, aciclovir or valaciclovir tablets may be prescribed by your GP. These medications are also considered safe at all stages of pregnancy. Other medicines are available to treat herpes but there is not sufficient scientific evidence to indicate safety in pregnancy.
Can valacyclovir cause miscarriage?
Miscarriage can occur in any pregnancy. Studies have not found an increased chance for miscarriage following acyclovir use.
Treatment with antiviral medications is recommended for pregnant women or women who are up to 2 weeks postpartum (including following pregnancy loss) with suspected or confirmed influenza and can be taken during any trimester of pregnancy.
How fast does valacyclovir work?
For most initial herpes outbreaks and cases of recurring herpes, valacyclovir takes effect very quickly and provides some level of relief in as little as two to three days. Generally, the sooner you take valacyclovir after noticing symptoms, the faster it will be to provide relief.
Can you take valacyclovir while nursing?
The American Academy of Pediatrics considers acyclovir to be safe during breastfeeding, according to the researchers. And the current study, the researchers say, confirms that Valtrex is not found in breast milk. They conclude that Valtrex is safe during breastfeeding.
What can acyclovir cause while being pregnant?
Acyclovir, an antiviral nucleoside analogue, is a widely used agent highly specific for herpes simplex and varicella-zoster viruses. Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety.
Does acyclovir pass through placenta?
Acyclovir is known to cross the placenta to the fetus. Frenkel et al4 reported the specific pharmacokinetics of acyclovir in pregnant patients with recurrent HSV receiv ing either 200 or 400 mg of acyclovir orally every 8 hours from 38 weeks’ gestation until delivery.
How can I reduce the side effects of valacyclovir?
Take valacyclovir by mouth, with or without food, as directed by your doctor. Drink plenty of fluids while taking this medication to lower the chance of side effects.
Is acyclovir cream safe in pregnancy?
Conclusion: Use of acyclovir in the first trimester does not increase birth defects, and it should be the antiviral drug of choice in early pregnancy.